Andrew Mayne, AI Keynote Speaker

OpenAI's original Science Communicator and first prompt engineer, Andrew helps leaders understand frontier AI capabilities and turn them into practical organizational capacity. As founder of Interdimensional and host of The OpenAI Podcast, he works with technical and executive audiences on AI adoption, team acceleration, and practical strategy, helping teams at Microsoft, John Deere, OpenAI, Deloitte, Aprio, Moelis, Eight Sleep, Evolutionary Scale, Tala, Kairo, and Prompt adapt to and utilize AI.

Andrew Mayne

AI, Creativity, Work

Andrew helps audiences understand artificial intelligence as a practical tool for building better teams, faster workflows, and more creative organizations. His talks connect firsthand experience inside OpenAI with the work Interdimensional does helping teams turn AI access into durable capability.

Event planners bring him in when they need a speaker who can make AI clear, useful, and energizing for executives, operators, creators, technical teams, and general audiences.

Talk Topics

Speaking inquiries

Building AI-Powered Teams and Accelerating Innovation

How leaders can move past AI demos and build teams that use intelligent tools in real workflows. Andrew shows organizations how to develop AI fluency, redesign daily work, and create a culture where focused teams can move faster and produce better outcomes.

Where AI Is Headed: An Insider's Perspective on the Next Decade

A grounded look at what is real, what is noise, and what leaders should prepare for now. Drawing from his time inside OpenAI and his work helping organizations adopt AI, Andrew explains how models, markets, and mindsets are changing.

How I Became OpenAI's First Prompt Engineer — and What It Taught Me About Building a Career in the Age of AI

A practical, human story about recognizing technological inflection points, turning uncertainty into momentum, and navigating the AI revolution with agency. This talk connects prompt engineering, creativity, and career reinvention.

Best For

  • Executive offsites
  • Corporate innovation events
  • Developer conferences
  • Media and entertainment teams
  • Education and learning programs

Event Fit

Andrew gives leaders and teams a practical language for deciding where AI helps, where human judgment matters, and how to accelerate innovation without losing quality.

Talks can be shaped for executive, technical, creative, media, education, and general audiences, with booking and availability handled through CAA.

FAQ

How do I book Andrew Mayne for a keynote or event?

Speaking availability and booking inquiries are handled through Andrew Mayne's CAA Speakers profile.

What audiences does Andrew speak to?

Andrew speaks to executive, corporate, technical, creative, media, education, and general audiences interested in practical artificial intelligence and technological change.

Can talks be customized for a company or conference?

Yes. Andrew's talks can be shaped around the audience, industry, event goals, and the level of AI familiarity in the room.

Does Andrew do virtual and in-person events?

Availability for virtual or in-person events is handled through CAA and depends on the event, schedule, and audience needs.